Uptodate Lexidrug

Medical · Wolters Kluwer Health UpToDate

Uptodate Lexidrug icon
4K ratings
4.3
Installs
1M+
Price
Free
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Uptodate Lexidrug screenshots

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Clinical decisions often hinge on details that are easy to misremember: a pediatric dose, a contraindication, the severity of an interaction between two drugs a patient is already taking. Pulling out a phone and finding a trustworthy answer in under a minute is the difference between a smooth consultation and a stalled one. Uptodate Lexidrug, from Wolters Kluwer Health UpToDate, is built for exactly that moment. It is a drug reference app that has been available on Android since April 2010.

The app was formerly known as Lexicomp, and the current name reflects its place in the UpToDate family of clinical resources. It has accumulated over a million installs and holds a 4.3 average from roughly four thousand ratings. Those numbers suggest a settled, widely used tool rather than a novelty. What follows is a look at what it offers, what it costs and who stands to benefit most.

What the app does and how it works

At its core, Uptodate Lexidrug is a reference library for medications. It offers drug databases covering dosing in detail, monographs that list adverse reactions, and a tool for checking interactions between drugs. There are also hundreds of medical calculators bundled in. The content is accessed directly within the app, so there is no need to download separate databases onto your device before you can look something up.

A team of editors from several fields reviews new evidence and refreshes the clinical content every day. That daily cadence matters in a field where labeling changes and new safety warnings appear regularly. The app is used by pharmacists, physicians, nurses, advanced practice nurses, dentists and students, which gives a sense of the breadth of its intended audience.

Several mobile packages are offered for different job roles. Which package you are on may affect what you see and can do. For a solo practitioner or a student, the practical effect is that the app is meant to be configured around a particular professional context rather than being a single one-size-fits-all reference.

Drug information, dosing and monographs

The drug databases are the heart of the app. Dosing support is described as detailed, which suggests it goes beyond a single standard adult figure and covers the kind of adjustments clinicians routinely need. Comprehensive monographs bring together adverse reactions and other clinical detail in one place. For a pharmacist verifying a prescription or a nurse double-checking a high-alert medication, having that depth on a phone is the main draw.

Because the content is accessed in-app rather than downloaded as a separate database, the experience is meant to be immediate. The developer also mentions the ability to store database content for offline use, which is useful in settings where connectivity is unreliable, such as a rural clinic or a hospital basement. That feature is stated as a capability, not a default, so it is worth checking how it applies to your package.

The monographs and databases are the sort of material that rewards familiarity. A new user will likely spend the first few sessions learning how the content is organized and where the answers to common questions live. That is not a flaw so much as the nature of a deep clinical reference; the payoff is that the information is there when you need it.

Interaction checks and medical calculators

The interactive drug interactions checker is the feature I would expect to get the most use in day-to-day practice. Polypharmacy is common, and a quick way to screen a medication list for potential problems is valuable at the point of prescribing or dispensing. You enter the drugs and the app returns the relevant interaction information.

Alongside that sit hundreds of medical calculators. These are the kind of tools that replace mental arithmetic or a separate app: renal function estimates, dose conversions and similar routine calculations. Having them in the same place as the drug data reduces the friction of switching between resources. The count suggests breadth rather than a precise inventory.

Together, the checker and the calculators round out the app beyond a simple drug dictionary. They make it a working tool for the moments when a decision is being made, not just a place to read up afterward. For clinicians who already rely on a paper or desktop reference, this is the part that translates most naturally to a phone.

What it requires and what to weigh

The app itself is free to download, and there are no ads. It does offer in-app purchases, and the main one is clear: new individual users receive a 14-day free trial of the Hospital Pharmacist package. Once that trial ends, the subscription renews automatically at $29.99 per month through the Google Play account unless it is canceled at least 24 hours before the trial period ends.

That is a meaningful recurring cost, and it is the single most important thing to understand before installing. Cancelation and auto-renewal settings are managed through Google Play subscription settings, and any unused portion of a free trial is forfeited when a subscription is purchased. If you are exploring the app out of curiosity, the trial clock starts immediately, so it is worth deciding early whether the package fits your needs.

The other consideration is the app's focus. It is a professional drug reference, and the depth of the monographs and dosing support is aimed at people who need that level of detail. A general reader looking for plain-language medication information would find the material dense and the subscription hard to justify. The app is also built around the assumption that you are using it in a clinical or academic context, which shapes both its content and its cost.

Who it suits

The clearest fit is a practicing clinician who already values a comprehensive drug reference: a pharmacist, physician, nurse practitioner or dentist who needs dosing detail, adverse reaction information and interaction screening during the working day. Students in these fields are also named among the users, and for them the app can serve as a learning companion, provided the subscription cost is manageable.

The offline storage option and the in-app access model make it practical for settings where you move between locations or work with unreliable connectivity. The daily updates are a point in its favor for anyone who needs to stay current with labeling changes and safety communications. The 4.3 rating from a large install base suggests that many users find it dependable.

It is less obviously suited to someone who only occasionally needs to look up a drug and would be better served by a lighter, free resource. The subscription is the gate, and the app's value scales with how often you need the depth it provides. For a clinician using it several times a week, the monthly fee is easier to justify than for a casual user.

A dependable reference for working clinicians

Uptodate Lexidrug is a mature, focused drug reference that does a specific job well. It brings together detailed dosing support, comprehensive monographs, an interaction checker and hundreds of calculators, with content updated daily. Access happens in the app, and there is an option to store content for offline use. The recent update streamlined navigation and improved the speed of getting to answers.

The trade-off is the subscription. That is a real commitment, and it makes the app best suited to professionals and students who will use it regularly in clinical or academic work. If that describes you, the depth and daily updates make a strong case. If you need only occasional drug information, the price is harder to justify.

The short verdict

A deep, daily-updated drug reference for clinicians, with a subscription that rewards frequent professional use.

What's new

- Boosted speed to answers with a redesigned 3/4 outline overlay - Streamlined navigation by relocating quick links to the bottom of the screen

App specs

  • VersionVaries with device
  • UpdatedMay 20, 2026
  • Downloads1M+
  • RequiresVaries with device
  • PriceFree
  • Age ratingEveryone

Uptodate Lexidrug: frequently asked questions

What is Uptodate Lexidrug used for?

It is a drug reference app that provides in-depth drug databases, detailed dosing support, comprehensive monographs with adverse reactions, an interactive drug interactions checker and hundreds of medical calculators. It is used by pharmacists, physicians, nurses, advanced practice nurses, dentists and students. You reach the content straight from the app, with no separate databases to download.

How much does Uptodate Lexidrug cost?

The app is free to download, but it offers in-app purchases. After the trial, the subscription is billed at $29.99 per month through Google Play unless canceled at least 24 hours before the trial ends.

Can I use Uptodate Lexidrug offline?

Database content can be stored for offline use. Database content can be stored for offline use. The app also lets you access content directly without downloading databases first.

How often is the drug information updated?

A team of editors from several fields reviews new evidence and refreshes the clinical content every day. That daily review cycle is intended to keep the monographs and dosing information current. It is one of the app's stated strengths for clinicians who need up-to-date safety and labeling details.

What changed in the most recent update?

A redesigned 3/4 outline overlay is meant to speed up getting to answers. Quick links were also relocated to the bottom of the screen to streamline navigation. These are interface adjustments rather than changes to the underlying drug content.

Pros

  • Detailed dosing support and comprehensive monographs
  • Interactive drug interactions checker built in
  • Hundreds of medical calculators in one app
  • Content accessed in-app, no database downloads
  • Option to store content for offline use

Cons

  • Then $29.99 per month
  • Auto-renews unless canceled 24 hours before trial ends
  • Content aimed at clinical professionals, not general readers

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